Abstract

We established a web-based ubiquitous health management (UHM) system, “ECG4UHM”, for processing ECG signals with AI-enabled models to recognize hybrid arrhythmia patterns, including atrial premature atrial complex (APC), atrial fibrillation (AFib), ventricular premature complex (VPC), and ventricular tachycardia (VT), versus normal sinus rhythm (NSR). The analytical model coupled machine learning methods, such as multiple layer perceptron (MLP), random forest (RF), support vector machine (SVM), and naive Bayes (NB), to process the hybrid patterns of four arrhythmia symptoms for AI computation. The data pre-processing used Hilbert–Huang transform (HHT) with empirical mode decomposition to calculate ECGs’ intrinsic mode functions (IMFs). The area centroids of the IMFs’ marginal Hilbert spectrum were suggested as the HHT-based features. We engaged the MATLABTM compiler and runtime server in the ECG4UHM to build the recognition modules for driving AI computation to identify the arrhythmia symptoms. The modeling extracted the crucial data sets from the MIT-BIH arrhythmia open database. The validated models, including the premature pattern (i.e., APC–VPC) and the fibril-rapid pattern (i.e., AFib–VT) against NSR, could reach the best area under the curve (AUC) of the receiver operating characteristic (ROC) of approximately 0.99. The models for all hybrid patterns, without VPC versus AFib and VT, achieved an average accuracy of approximately 90%. With the prediction test, the respective AUCs of the NSR and APC versus the AFib, VPC, and VT were 0.94 and 0.93 for the RF and SVM on average. The average accuracy and the AUC of the MLP, RF, and SVM models for APC–VT reached the value of 0.98. The self-developed system with AI computation modeling can be the backend of the intelligent social-health system that can recognize hybrid arrhythmia patterns in the UHM and home-isolated cares.

Highlights

  • We developed a prototype of a ubiquitous health management (UHM) system (UHMS) and conducted an an artificial intelligence (AI) computation with multiclass recognition models composed of the machine learning (ML) methods (e.g., AI computation with multiclass recognition models composed of the ML methods (e.g., multiple layer perceptron (MLP), random forest (RF),support vector machine (SVM), SVM,and andNB)

  • The ML models due to the crucial data set for the normal sinus rhythm (NSR) versus both the premature pattern (i.e., atrial premature complex (APC) and ventricular premature complex (VPC)) and the fibril-rapid pattern (i.e., atrial fibrillation (AFib) and ventricular tachycardia (VT)) were approved by cross-validation

  • The Hilbert–Huang transform (HHT) process retrieved the features regarding the symptoms of APC, AFib, VPC, VT, and NSR from the sample data sets

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Summary

Introduction

In the artificial intelligence (AI) era, ubiquitous health management (UHM) and care services have been made to be compliant with smart medical techniques. Physiological signals can be routinely tracked by wearable sensors at home for clinical diagnosis of chronic diseases (e.g., arrhythmia) and even home-isolated cares (e.g., COVID-19) [1,2]. Medical informatics with AI computation can be targeted in a recognition model to efficiently identify clinical data characteristics for health risk assessment and prevention [3,4,5]. The AI-enabled machine learning (ML) model typically consists of featuring and data training, which pre-processes the labeled samples (e.g., specific symptoms in the electrocardiogram (ECG) of arrhythmia) and explores the features to recognize clinical data [6,7,8]. Hybrid ML methods were qualified for coupling analysis of comprehensive features

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