Hybrid Materials from Electropolymerized Thin Polymer Layer - Based Electrodes for the Elaboration of a New Generation of Electrochemical Sensors of NO in Solution

Abstract

The measurement of nitric oxide NO is important for direct examination of its regulatory roles in biological systems and the major important criteria in making NO electrochemical sensors are the design of electrode arrays having various arrangements. Electrodeposited nickel phthalocyanine films on electrodes brought a substantial contribution to the development of efficient sensors, but such surface modification suffers from the highly corrosive media used for the nickel complex and instability. We explore here the possibility of developing soft methods to chemically modify the electrode surface. We report on preliminary results obtained with Pt ultramicroelectrodes modified with electropolymerized phenol, eugenol, o-phenylene diamine and aniline thin layers in aqueous solution at pH 7.4. The sensitivity towards NO and the selectivity of the obtained electrodes against biologically relevant interfering analytes (nitrite, ascorbate, dopamine and hydrogen peroxide) are analyzed by chronoamperometry.