Abstract
A facile CO-release material for in-situ vasodilation as a treatment for stroke-related vascular diseases is developed by K.V. Kong, L.D. Liao and co-workers in article number 1701113. Utilizing the size dependent adsorption properties of ruthenium carbonyl clusters (Ru-CO) onto graphene oxide (GO), the rate and amount of formation of the CO release-active RuII(CO)2 species can be modulated by a simple mixing procedure. Further modulation of thermal and CO release properties can be achieved via a hybridization of medium- and high- nuclearity of Ru-CO clusters that can provide photo-thermal response for in-situ CO release in a cortical photo-thrombotic ischemia rat model.
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