Abstract
Numerical simulations based on the classical Marmarou’s model have been carried out to analyse the dynamics of hydrocephalus valves. The evolution of the intracranial pressure in various case studi...
Highlights
Hydrocephalus is caused by a pathological accumulation of cerebrospinal fluid in the brain ventricles
The flow control valve is able to drain the ICP at the production rate without low ICP periods when the hydrostatic pressure matches perfectly the device characteristics provided in Figure 1(c) (HP < 250 mm H2O)
Impact of the resistance to reabsorption on the functioning of flow control and hybrid valves It could be noticed that such flow control valves may exhibit a permanent increase of ICP in decubitus in case of high resistance to reabsorption and cerebrospinal fluid (CSF) production rate larger that the nominal value
Summary
Hydrocephalus is caused by a pathological accumulation of cerebrospinal fluid (hereafter CSF) in the brain ventricles. Thanks to the presence of the peak of flow rate at low pressure (see Figure 1(d)), short term fluctuations around the nominal value due to the vasogenic system, or inter-individual variations of production rate in the range 20 ± 4 mL/h, have a very limited impact on ICP value, even for patients having a very large resistance to CSF reabsorption (e.g. in case of obstructive hydrocephalus).
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