Abstract
Production of hyaluronidase by 147 strains of beta hemolytic streptococci was studied employing a sensitive dye-binding assay and levels of enzyme activity were evaluated statistically. The analysis of variance showed that group A strains isolated in Rio de Janeiro produced significantly smaller amounts of enzyme than group A strains from a Minneapolis (USA) collection or than groups B and G brazilian isolates. The t test revealed that M not typable nose/throat group A strains produced more hyaluronidase than skin isolates. The analysis of variance did not show a significant difference in the enzyme production between M typable and not typable brazilian strains of group A streptococci. High enzyme — producing strains were not restricted to a few serotypes of group B streptococci.
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