Abstract
Hyaluronidases are applied to break hyaluronic acid found in high levels in the cumulus-oocyte complex at the oocyte denudation for in vitro fertilization (IVF). The purpose of the study was to investigate whether midkine (MK) has a role at the proliferation and viability of cumulus cells (CCs) at the oocyte denudation done by using hyaluronidase.
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