Abstract
A SUBSTANCE liquefying the jelly-coat of sea-urchin eggs was first recovered from the sperm of sea-urchins by Hartmann and Schartau1, who called it 'Androgamone II'. The enzyme nature of this substance was, however, denied2; moreover, it was pointed out that hyaluronidase from bull testis does not dissolve the jelly-coat of sea-urchin eggs3. On the otber hand, an enzyme preparation from Clostridium oed. mal. was found to dissolve it4.
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