Hyaluronic Acid and Platelet Rich Plasma in Hip Osteoarthritis: Work in Progress

Abstract

In OA, the concentration and the molecular weight of HA are reduced, resulting in synovial fluid of lower elasticity and viscosity: diluitional effects, reduced hyaluronan synthesis and free radical degradation are the factors which contribute to the lower concentrations of HA. When the visco elasticity of synovial fluid is reduced, the transmission of mechanical force to cartilage may increase its susceptibility to mechanical damage [2].