Abstract

Today sintering of inflow cannulae in left ventricular assist devices (LVAD) is accepted as standard to ensure good myocardial ingrowth, preventing thrombus formation at the apical penetration site. Various studies like the ADVANCE trial compared the formerly polished pump of the HeartWare HVAD and the sintered version commercialized since 2012, investigating the incidence of pump thrombosis and thromboembolic complications. Though this is of essential clinical importance, it is only a surrogate for inflow cannula thrombus development.

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