Humidity and pH dual-responsive smart nanofiber antimicrobial packaging

Abstract

Smart antimicrobial active packaging, capable of responsive release of antimicrobial agents under environmental stimuli, has garnered widespread attention in recent years. This study developed an intelligent active packaging, Cin@PVA/CS-Cin nanofiber films via electrospinning, that exhibits dual-stimuli responsiveness for the release of cinnamaldehyde (Cin) antimicrobial agent. This packaging can respond by releasing Cin in a high-humidity environment during fruit storage to inhibit microbial proliferation. Additionally, in the event of Botrytis cinerea colonization causing a pH decrease, it can further respond by releasing Cin to prevent more fruits from being colonized. Experimental results proved that the Cin@PVA/CS-Cin nanofiber film exhibits excellent humidity and pH responsive capabilities for Cin release, along with outstanding pH-responsive antibacterial and antifungal activity. The preservation experiment on strawberries has confirmed that the film effectively extends the shelf life of strawberries. The enhanced stability and improved antimicrobial performance of this more intelligent multi-responsive antimicrobial active packaging hold significant importance for its practical application in complex environments.