Abstract
FMD control is largely based on regular vaccination to reduce disease and transmission, in this work we have examinedthe influence of single vaccination and the interval between the first and second vaccinations , the cattle were allotted into4 groups and vaccinated with inactivated concentrated and purified FMD vaccine in different programmes of vaccination,it was found that The double doses vaccination two months interval by polyvalent inactivated concentrated and purified oiladjuvant FMD vaccine enhance the afforded protection duration for vaccinated cattle(prolonged immunity), also this programprovide the vaccinated animals with high protective antibody titer thus high protection against challenge test
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