Abstract
Objectives: The present study was designed to know the possible protective and regenerative effects of human Umbilical Cord Blood (UCB) derived MSCs in Myocardia Infarction (MI) in rat model using Isoproterenol administration. Material & methods: Isoproterenol injection was given subcutaneously for 2 days to induce MI in rat model. After development of MI various blood and tissue parameters were assessed sich as urea, creatinine, SGOT, SGPT, troponin I, Lactic Dehydrogenase (LDH) and Creatine Kinase (CK). Treatment was given by single dose of MSCs. After treatment period all the parameters were assessed again and comparison were done before and after treatment.
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