Abstract
High dynamic range optical-to-near-infrared transmission measurements for different parts of human body in the spectral range from 650 to 950 nm have been performed. Experimentally measured spectra are correlated with Monte Carlo simulations using chromaticity coordinates in CIE 1976 L*a*b* color space. Both a qualitative and a quantitative agreement have been found, paving a new way of characterizing human tissues in vivo. The newly developed experimental and computational platform for assessing tissue transmission spectra is anticipated to have a considerable impact on identifying favorable conditions for laser surgery and optical diagnostics, while providing supplementary information about tissue properties.
Highlights
The spectral and colorimetric studies of biological tissues are of a considerable interest from the point of view of potential development of new techniques for non-invasive in vivo imaging and spectroscopic characterization of biological and human tissues and monitoring variations of their properties without amending their physiological state [1,2,3]
There were numerous attempts to evaluate optical tissue properties by assessing both scattering and absorption properties of tissues
We performed the pilot experimental studies of the near-IR spectral transmission measurements through a bulk tissue samples in vivo. Those results provide a quantitative measure of the light transmitted through a certain body area as a function of the incident wavelength in the biologically significant optical transmission window
Summary
The spectral and colorimetric studies of biological tissues are of a considerable interest from the point of view of potential development of new techniques for non-invasive in vivo imaging and spectroscopic characterization of biological and human tissues and monitoring variations of their properties without amending their physiological state [1,2,3]. This is especially important for a number of practical applications including medical diagnostics [4], plastic surgery [5], face recognition for security needs [6], as well as for the optical design of a particular diagnostic system. The computational data are compared with the experimental data obtained using high-dynamic range spectral transmission measurements through different parts of a human body, which are accessible through those measurements
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