Abstract
A higher incidence of XX embryos derived from IMSI (69.9%) compared to ICSI (52.5%) has been reported. Moreover, a significant difference (P<0.05) in the sex ratio of females to males at live birth has been demonstrated between children from IMSI (1.17) and the general population (0.95). However, spermatozoa with nuclear vacuoles seem to present higher chromosome abnormalities compared to normal spermatozoa, but this result is controversial. This study evaluated the impact of selecting morphological normal spermatozoa using motile sperm organelle morphology examination (MSOME) on sex ratio and numerical chromosome anomalies.
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