Abstract
Human Pythiosis
Highlights
The first patient was a 63-year-old woman with hemoglobin AEBart’s disease, a complex thalassemia/ hemoglobinopathy syndrome, which required frequent blood transfusions
The patient reported frequent swimming in standing water in rice fields. He was febrile with a leukocyte count of 26,000/mm3 and was given broadspectrum intravenous antimicrobial agents
Serum antibodies to P. insidiosum by immunodiffusion were detected in both cases
Summary
The first patient was a 63-year-old woman with hemoglobin AEBart’s disease, a complex thalassemia/ hemoglobinopathy syndrome, which required frequent blood transfusions. Itraconazole solution, terbinafine, and therapeutic vaccines [3] were administered. Extended-spectrum antimicrobial agents were given during her hospital stay to combat nosocomial infections. The second patient was a 15-yearold boy with β-thalassemia/hemoglobin E disease, 10 years after splenectomy.
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