Abstract

s1 November 1965Human Pulmonary Infarctions and Surfactant Production.Alton I. Sutnick, M.D., Louis A. Soloff, M.D.Alton I. Sutnick, M.D.Search for more papers by this author, Louis A. Soloff, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-5-919_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been implied that an intact pulmonary arterial circulation is required for the production of pulmonary surfactant by the alveolar epithelial cells. Pulmonary infarctions in dogs have been shown to demonstrate a decrease in surface activity, but similar findings in human lungs have not been described. In order to evaluate this phenomenon in human lungs, we have studied 19 pulmonary infarctions found at autopsy. Saline extracts were made of all specimens, and surface activity was measured on a modified Langmuir-Whilhelmy surface film balance. Only one (5.3%) demonstrated a minimal surface tension below 10 dynes/cm, a consistent finding in 21... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1965Volume 63, Issue 5Page: 919-919KeywordsAutopsyEpithelial cellsInfarctionLungs Issue Published: 1 November 1965 PDF downloadLoading ...

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