Human papillomavirus deoxyribonucleic acid in adenocarcinoma and adenosquamous carcinoma of the uterine cervix : Smotkin D; Berek JS; Fu YS; et al. Division of Gynecologic Oncology, The Department of Microbiology and Immunology, UCLA School of Medicine, Los Angeles, CA, USA Obstet. Gynecol.; 68/2 (241–244) 1986

Abstract

This report describes the detection of human papillomavirus type 16 or 18 deoxyribonucleic acid (DNA) in nine of 15 invasive tumors of the cervix, including three squamous carcinomas, four adenosquamous carcinomas, one glassy cell carcinoma, and one adenocarcinoma. The viral DNA was identified by Southern blotting and DNA hybridization. Human papillomaviruses may play an etiologic role in the development of at least some adenocarcinomas and adenosquamous carcinomas as well as most squamous tumors of the cervix.