Abstract

BACKGROUND: Oral lichen planus is a chronic disease with periods of exacerbations and remissions, requiring long-term symptomatic treatment and observation. Dermatosis can occur or worsen in the presence of different triggers, for example, due to the persistence of the human papillomavirus.
 AIM: to explore the effect human papillomavirus on the characteristics oral lichen planus.
 MATERIALS AND METHODS: 90 patients with oral lichen planus aged from 26 to 73 years (average age 55.61±1.00 years) were examined. Real-time polymerase chain reaction was used to detect human papillomavirus. The need for treatment of caries, Green–Vermillion and complex periodontal indices were used to analysis state of oral hygiene.
 RESULTS: Human papillomavirus DNA was detected in 53 (58.88%) cases. Patients of this group were 4 years younger than other study participants; the duration of dermatosis is 2 years longer with a predominance of atrophic/erythematous and erosive/ulcerative forms. It was noted that indexes of caries and the complex periodontal were significantly (p=0,007 and p=0,030 respectively) higher compared to patients without papillomavirus infection.
 CONCLUSION: It is found features of oral lichen planus in identifying human papillomavirus: early onset; severe of the disease with predominantly destructive forms; high prevalence of caries and periodontitis.

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