Human Monkeypox and Human Immunodeficiency Virus Co-infection: A Case Series in Makurdi, Benue State, Nigeria

Po Echekwube,Oa Abidakun,Bt Utoo,Tz Swende,Pt Mbaave

doi:10.46912/jbrcp.184

Po Echekwube, Oa Abidakun + Show 3 more

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https://doi.org/10.46912/jbrcp.184

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Abstract

The Human monkeypox is a viral zoonosis which was first reported as a human disease in Zaire (present day Democratic Republic of Congo) in 1970. Outbreaks of the disease have occurred, though rarely, in some West African countries including Nigeria since then. However, in 2017 there was a large outbreak in Nigeria affecting a lot of states. We wish to report the cases that were identified and managed successfully in Makurdi, Benue state because of their unique presentation as all but one of the patients had HIV coinfection which possibly was a risk factor for the monkeypox viral infection

Highlights

The Human monkeypox is a zoonotic disease which is caused by the Monkey Pox Virus (MPXV), a member of the genus Orthopoxvirus.[1]
Monkeypox was first reported as a human disease in a 9 month old child from Zaire in 1970 and most of the information in literature about human monkeypox came from the investigations of outbreaks in central and western Africa.[2]
Animal-to-human transmission may occur by animal bite or scratch, bush meat preparation, direct contact with body fluids or lesion material, or indirect contact with lesion material

Summary

INTRODUCTION

The Human monkeypox is a zoonotic disease which is caused by the Monkey Pox Virus (MPXV), a member of the genus Orthopoxvirus (family Poxviridae, subfamily Chordopoxvirinae).[1]. CASE 3 A 40 year old female trader who presented to our facility with numerous cutaneous eruptions (papules, pustules and nodules) limited to her lower extremities and covered about 20% of her Total Body Surface Area (Fig 1c) She had a low-grade fever, headaches and anorexia which commenced 3 days prior to the onset of the eruptions and continued till presentation. A 32year old female trader who presented to our facility with a history of fever for 2 weeks and cutaneous eruptions (papules, pustules and nodules) on the trunk and extremities for 1 week Most of her lesions were on the dorsum of the hands (Fig 1d) There was no recent history of travel nor contact with anyone with similar lesions. There were residual scars and postinflammatory hyperpigmented macules and patches

DISCUSSION

Findings

CONCLUSION