Abstract
1. Introduction - a disease for every gene? Part I. From Molecular Biology to Human Genetics: 2. Biomolecular evolution 3. Chromatin and chromosomes 4. Gene expression 5. RNA processing and translation 6. Protein structure and function Part II. From Molecular Genetics to Human Biochemistry: 7. Nutrition and energy 8. Membranes and channels 9. Cell surface receptors 10. Adhesion molecules and the extracellular matrix 11. Cytoskeletal and motor proteins Part III. From Molecular Biochemistry to Human Cell Biology: 12. Signal transduction 13. Inflammatory cytokines 14. Hormones and growth factors 15. Hemopoietins, angiogenins and vasoactive mediators 16. Cell cycle control, apoptosis and ageing Part IV. From Molecular Cell Biology to Human Physiology: 17. Development 18. Metabolism 19. Blood 20. Immunity 21. Neurobiology Part V. From Molecular Physiology to Human Molecular Biology: 22. Genetic test systems 23. Gene and protein analysis 24. Genetic engineering, gene mapping and gene testing 25. Gene knockouts, transgenics, and cloned animals 26. Gene therapy and recombinant DNA technology Index.
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