Human mannan binding protein in pre-eclampsia

Abstract

Mannan binding protein (MBP) was measured in the sera of 95 patients with proteinuric pre-eclampsia and in 76 sera from the husbands of those patients. No significant difference was found in comparison with 352 blood donors. However, couples experiencing recurrent pre-eclampsia had significantly lower levels of MBP than those associated with primiparous couples with pre-eclampsia. The latter finding was derived from data inspection and not from a prior hypothesis, and therefore requires independent confirmation preferably from a larger series.