Abstract
Glucocorticoid receptor levels and steroid induced inhibition of nucleic acid precursors incorporation have been determined in circulating lymphocytes of healthy donors on subpopulations isolated by immunoabsorbant column and density gradient centrifugation. The number of steroid binding sites and the affinities of the receptors for the tracer are not significantly different in B and T + Null cells fractions. [ 3H]-uridine incorporation tends to be in general more sensitive to steroid action in B cells than in T + Null cells, whereas the situation is reversed for [ 3H]-thymidine.
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