Abstract
Objective: To compare the epidemiological, the clinical and the paraclinical profile of osteoarticular infections in HIV-positive patients and in HIV-negative patients. Patients and Methods: patients with Osteoarticular infections recognized on the basis of radioclinical and epidemiological arguments were included in this study. The comparison that was based on the existence or was not of HIV infection focused on various clinical and biological components. Of these 15,800 rheumatic patients admitted in 18 years, 461 have suffered from Osteoarticular infection (2.9%). The 461 patient objects of this study were divided into 235 cases of infectious arthritis including 38 cases of co-infection with HIV and 225 cases of infectious spondylodiscitis including 21 cases of HIV co-infection. Results: There were 246 women (53.4%) and 215 men (46.4%) with a sex ratio of 1.1. The mean age was 37.7 ± 13.6 years. The data comparison of HIV-negative patients and HIV-positive patients had not shown statistically significant difference in the infectious spondylodiscitis group and in the group of infectious arthritis patients. Only fever was statistically significant in both groups and weight loss in the group of infectious arthritis (p < 0.001). Conclusion: HIV seems not to particularly influence the semiological profile of Osteoarticular infections in Lomé.
Highlights
Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) is a challenge for the world and a major problem of public health in sub-Saharan Africa
It is stated in these reports that personal characteristics other than HIV infection may have played a role in the pathogenesis of these infections, less frequent osteoarticular infections remain one of the daunting complications of infection to human immunodeficiency virus
The series included all patients diagnosed with infectious spondylodiscitis or septic arthritis in which retroviral serology was carried out systematically
Summary
Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) is a challenge for the world and a major problem of public health in sub-Saharan Africa. Many rheumatologic manifestations were described during HIV infection and several prospective cross-sectional studies allow assessing the prevalence of. (2014) Human Immunodeficiency Virus Can Affect the Semiology of Osteoarticular Infections? Other studies report osteoarticular infections as rare manifestations in HIV-infected patients, with 14 cases (0.3%) found among 4023 patients [7] and 23 cases found among 1515 patients [12]. It is stated in these reports that personal characteristics other than HIV infection may have played a role in the pathogenesis of these infections, less frequent osteoarticular infections remain one of the daunting complications of infection to human immunodeficiency virus. HIV/AIDS is responsible for various complications during its evolution and can change the course and clinical manifestations of some diseases [4] [7]. The aim of this study was to compare respectively semiological aspects of the spondylodiscitis and the infectious arthritis in HIV-infected patients to those patients who are not HIV infected
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