Abstract

We present an infant with acute fever, thrombocytopenia, and leukopenia, coming from an endemic region for tick-borne encephalitis, human granulocytic anaplasmosis, and hantavirus infection. The primary human herpesvirus 6 infection was diagnosed by seroconversion of specific IgM and IgG and by identification of viral DNA in the acute patient's serum. The patient did not show skin rash suggestive of exanthema subitum during the course of illness.

Highlights

  • A Central European country, is an endemic region for at least three zoonotic infectious diseases that may present as an acute febrile illness associated with thrombocytopenia and leukopenia: tick-borne encephalitis (TBE), human granulocytic anaplasmosis, and hantavirus infection [1, 2]

  • We present a patient with exanthema subitum without exanthema, mimicking the three zoonotic infectious illnesses mentioned above

  • Only 17% of infants and young children with primary Human herpesvirus 6 PCR (HHV-6) infection have a rash, Case Reports in Pediatrics

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Summary

Introduction

A Central European country, is an endemic region for at least three zoonotic infectious diseases that may present as an acute febrile illness associated with thrombocytopenia and leukopenia: tick-borne encephalitis (TBE), human granulocytic anaplasmosis, and hantavirus infection [1, 2]. We present a patient with exanthema subitum without exanthema, mimicking the three zoonotic infectious illnesses mentioned above

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