Abstract

Summary A “hypopituitary” dwarf was treated during a 10-month period with human growth hormone (Raben12); there was a resultant spurt in growth associated with relatively slight, if any, maturation in body proportions and skeleton. Radiologic evidence of widening of the epiphyseal plates was noted. A constitutional or primordial dwarf was treated with similar amounts of growth hormone and failed to show significant reduction in urine nitrogen, changes in blood chemistries, or a spurt in linear growth. Neither patient had any apparent adverse reaction to the growth hormone.

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