Abstract

Diabetic cardiovascular complications (DCC) affecting the important organ systems of human body - cardiovascular system contributes a major public health problem. There is evidence demonstrating that genetic factors contribute to the risk of DCC. Genetics variants, structural variants play important roles in the development of DCC. In addition, mitochondrial DNA plays critical roles in regulation of development of DCC. This review focused on the current knowledge of the genetic basis of DCC. Ultimately, identification of genes or genetic loci, and structural variants associated with DCC will be for the benefit of the development of personalized medicine in diabetes mellitus and it complications.

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