Abstract
Three classes of Fc receptor for IgG have been defined: FcγRI, FcγRII and FcγRIII. FcγRII is the most widely distributed, but it has a low affinity for human IgG and its function is not well understood. In this and the following paper, two possible functions of FcγRII are presented. Here, Wil Tax and Jan van de Winkel argue that FcγRII may contribute significantly to FcγR-mediated processes, such as the removal of immune complexes and antibody-coated particles, especially in view of the recent finding that the affinity of FcγRII can be upregulated by proteolysis. The following paper considers the role of FcγRII in the context of immune complex regulation of the immune system.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
