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Abstract
Soluble extracts of plaque from adults with periodontitis and children without evidence of destructive periodontal disease stimulated bone resorption in tissue culture. This effect was associated with the formation of osteoclasts. The extracts did not stimulate resorption of heat-devitalized bones. The bone resorptive factor in plaque behaved the same as purified endotoxin by two criteria: resistance to boiling and non-dialysability.
Published Version
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