Abstract
The possibility of simulating a free-running 24-h sleep-wake cycle was studied in the group of three subjects under rigid motivation conditions, including a strictly specified sleep time in a free daily routine. In this case, the effect of motivation-dependent social timer (clock) on synchronizing the human 25-h circadian rhythm was studied depending on the individual typological features; whereas the test subjects were not socially isolated and the main biotic and abiotic timers had a 24-h cycle. The typological features of subjects (predominant vagotonia, sympathotonia, normotonia) were studied that provide or limit the circadian rhythm synchronization of the vegetative functions by changing the sleep-weake rhythm (behavioral rhythm). Melatonin administration was shown to be effective in both sympathotonics and normotonics.
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