Abstract

Zoonotic infections with swine influenza A viruses are reported sporadically. Triple reassortant swine influenza viruses have been isolated from pigs in the United States since 1998. We report a human case of upper respiratory illness associated with swine influenza A (H1N1) triple reassortant virus infection that occurred during 2005 following exposure to freshly killed pigs.

Highlights

  • Human infections with swine influenza A viruses occur sporadically in the United States and Canada [1,2,3,4,5,6,7,8]

  • We report a human case of swine influenza A (H1N1)

  • Swine influenza A/Wisconsin/87/2005 (H1N1) virus was isolated from an upper respiratory specimen obtained from the patient, and serologic testing suggested, but was not diagnostic of, an immune response to acute infection

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Summary

Introduction

Human infections with swine influenza A viruses occur sporadically in the United States and Canada [1,2,3,4,5,6,7,8]. The specimen was sent to the Wisconsin State Laboratory of Hygiene (WSLH), and an influenza A virus was isolated by shell vial tissue cell culture (MDCK cells, WSLH, Madison, WI, USA). At the Centers for Disease Control and Prevention (CDC), rRT-PCR testing of the shell vial viral culture material was positive for influenza A virus, but negative for human subtypes H1 and H3, as well as avian subtypes H5, H7, and H9.

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