Human Cadaver Homograft in Toxic Epidermal Necrolysis

Abstract

Burn-unit management is described of severe drug-induced toxic epidermal necrolysis, with 90% skin and mucosal involvement. In this patient, in whom acidosis and sepsis complicated the case, wound coverage with heterograft was ineffective but cadaver skin homograft “take” occurred and the wound was closed. Some homograft remained on the healthy patient at 5 months after discharge.