Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen.

Deborah A Shackelford,G B Ferrara,Jon J Van Rood,Dean L Mann,Jack L Strominger

doi:10.1073/pnas.78.7.4566

Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen.

Deborah A Shackelford, G B Ferrara + Show 3 more

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https://doi.org/10.1073/pnas.78.7.4566

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Journal: Proceedings of the National Academy of Sciences of the United States of America	Publication Date: Jul 1, 1981
Citations: 270

Affiliation: Harvard University, Leiden University Medical Center, National Institutes of Health, National Cancer Institute

#Human B-lymphoblastoid Cell Lines #HLA-DR Antigen + Show 8 more

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Abstract

Some human B-lymphoblastoid cell lines are shown to express at least two types of Ia-like antigens. One antigen is defined by alloantisera to HLA-DR, and the other antigen is defined by alloantisera and a monoclonal antibody to the specificities DC1, MT1 (MB1), and LB12, which are in linkage disequilibrium with HLA-DR. The subunits of the DC1 molecule differ from those of the DR molecule. The light chains of both molecules are structurally polymorphic.

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