Abstract
Outbreaks of acute respiratory disease associated with human adenovirus (HAdV) B7d have been reported, including fatal cases in the United States. In 2018, we detected HAdV-B7d in a patient with urethritis, probably transmitted through sexual contact. Infectious HAdV-B7d was excreted in urine and gargle for >10 days after the disappearance of symptoms.
Highlights
Outbreaks of acute respiratory disease associated with human adenovirus (HAdV) B7d have been reported, including fatal cases in the United States
In 2011, HAdVB7d was prevalent throughout Asia, and outbreaks of infant pneumonia related to HAdV-B7d were reported in China [5,6,7]
In Japan, routine national surveillance for HAdVs is conducted for epidemic keratoconjunctivitis, pharyngeal conjunctival fever, and infectious gastroenteritis, and reported in the Infectious Diseases Weekly Report [8]
Summary
Outbreaks of acute respiratory disease associated with human adenovirus (HAdV) B7d have been reported, including fatal cases in the United States. HAdVB7d has been more commonly associated with severe respiratory disease and has a higher mortality rate than other HAdV types [6,12]. The Study Since 2013, we have focused on HAdV-associated urethritis and performed pathogen screening from the urine of all-male patients with acute urethritis at iClinic in Sendai City, Miyagi Prefecture, Japan; all patients gave informed consent (reference 16 in Appendix, https://wwwnc.cdc.gov/EID/26/10/19-1538App1.pdf).
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