Hubungan Kadar HbA1c Dengan Kadar Serum Kreatinin Pada Penderita Diabetes Melitus Tipe 2 Di RSU Sinar Kasih Purwokerto

Abstract

Diabetes Mellitus is a metabolic disorder caused by a decrease in insulin products in the body. The World Health Organization estimates an increase in the number of diabetes mellitus sufferers from 8.4 million in 2000 to around 21.3 million in 2030. Chronic diabetes mellitus sufferers can cause complications, one of which is kidney complications. Kidney damage can occur due to uncontrolled blood sugar levels. Complications of diabetes mellitus can be detected by examining HbA1c. HbA1c is a non-enzymatic binding of glucose molecules to hemoglobin through a post-translational glycation process. Uncontrolled HbA1c levels can cause various complications in the body.The samples used for this research were 106 samples with normal HbA1C examination results, namely 59 patients and high results, namely 47 patients. Creatinine examination with normal results was 81 patients and high results were 25 patients. The P-value from the calculation results is 0.066 higher than 0.005. Based on the results of the chi square calculation, it can be concluded that there is not a relationship between HbA1C examination and creatinine examination in type 2 diabetes mellitus patients at Sinar Kasih Hospital.