Huai qi huang granules for the treatment of children with mycoplasma pneumoniae pneumonia: a multi-center clinical study

Abstract

Objective To analyze the effects of Huai qi huang granules on children with mycoplasma pneumoniae pneumonia. Methods A randomized, multicenter parallel controlled clinical trial was carried out.A total of 3 000 cases of hospitalized children with mycoplasma pneumoniae pneumonia were selected.All of them were given treatment for mycoplasma pneumoniae pneumonia with macrolide antibiotics and symptomatic treatment.They were randomly divided into 2 groups: research group and control group.The children of research group were give oral Huai qi huang granules for three months.According to the classification of pneumonia, these two groups were divided into: lobar pneumonia research group, lobar pneumonia control group, lobular pneumonia research group, lobular pneumonia control group.The hospitalization duration of fever, length of hospital stay, the absorption area of lung inflammation and pneumonia severity sores were observed.The frequency of upper respiratory infections, bronchitis, pneumonia were observed in 3 months after discharge. Results 2 378 cases were investigated.The hospitalization duration of fever, length of hospital stay of research group were significantly shorter than that of in control group(P 0.05). Conclusion Standard treatment combined with oral Huai qi huang granules in the treatment of mycoplasma pneumoniae pneumonia, can significantly shorten hospitalization duration of fever, length of hospital stay and reduce the severity score of pneumonia.Three months oral Huai qi huang granules can significant reduce the frequency of respiratory infections and bronchitis, also can increase patients appetite, and be safe. Key words: Mycoplasma pneumoniae pneumonia; Huai qi huang granules; Children; Randomized controlled trial; Multicenter study