HSD14 Lacking Observance of the Guidelines on Dyslipidaemias as Possible Reason for Low LDL-C Goal Attainment in Patients at High and Very High Cardiovascular Risk

Abstract

Several studies have clearly demonstrated the causative role of increased plasma concentrations of LDL-C in the process of atherosclerotic plaque formation. These findings have been reflected in the updated guidelines for the management of dyslipidaemias, proposing new stringent LDL-C goals and treatment algorithm. Although the evidence is quickly translated into the guidelines, there still exists a large gap between recommendations and real clinical practice. The objective of the study was to investigate the adherence of Czech cardiologists to the dyslipidaemias guidelines, especially in the management of patients with high- and very-high cardiovascular risk.