HRCT Lung in a Follow up Patients of Bone Marrow Transplant with Cough and their Pathological Correlation

Abstract

Introduction: Bone marrow transplantation is today’s procedure of choice for management of various malignancies and immunologic disorders. HRCT is the common technique in the diagnosis of such recipient’s with respiratory symptoms. This study we will target the accuracy of the modality and its pathological correlation. Aim To study the role of HRCT in transplant patients with respiratory symptoms and their pathological correlation. Material and Methods Patients are screened for pre transplant chemotherapy, clinical examination, lab investigations including blood and biochemical examinations, radiological examinations and a follow up for post transplant infections and complications with 16 slice Siemens CT scan. Result Study included total 52 patients The patients presented early symptoms (<30 days) and findings were associated with prolonged neutropenia and later excluded due to non-engraftment. Conclusion: Study claims pick up of findings on the HRCT which were not seen on routine chest radiograph and confirmed pathologically. This study suggests use of HRCT for early diagnosis.