HPV knowledge and vaccine acceptance among European adolescents and their parents: a systematic literature review

Noelia López,Maria Garcés-Sánchez,Beatriz Ramos,Maria Teresa Artés,Manuel Cotarelo,Maria Belén Panizo,Ignacio Salamanca de la Cueva

doi:10.1186/s40985-020-00126-5

Noelia López, Maria Garcés-Sánchez + Show 5 more

Open Access

https://doi.org/10.1186/s40985-020-00126-5

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Abstract

BackgroundSince the introduction of HPV vaccines, several studies have been conducted in different countries to assess HPV knowledge and vaccine acceptance. The aim of this study was to perform a systematic literature review to summarize results and identify factors associated with HPV knowledge and vaccine acceptance in adolescents and their parents and to compile the measurement tools used in the published research studies performed in European countries where HPV is licensed.MethodsA systematic literature review was conducted for studies published between January 1st 2006 and December 31st 2017.ResultsSeventy non-interventional studies performed in 16 European countries met the inclusion criteria. Thirty-eight of them reported data on HPV knowledge and 40 reported data on HPV vaccine acceptance. Further, 51.8% of adolescents (range 0% to 98.6%) and 64.4% of parents (range 1.7% to 99.3%) knew about HPV infection. Insufficient information and safety concerns were the main barriers to vaccination acceptance.ConclusionHPV knowledge and vaccine acceptance are still modest and vary widely between studies across EU countries. Coordinated efforts should be made to provide the relevant population with information for informed decision-making about HPV vaccination.

Highlights

Since the introduction of Human Papillomavirus (HPV) vaccines, several studies have been conducted in different countries to assess HPV knowledge and vaccine acceptance
We reviewed all the scientific literature published between January 1st, 2006 and December 31st, 2017 to identify studies evaluating parental and/or adolescent HPV knowledge and/or acceptance of HPV vaccination
– Population: only studies performed in parents of children of any age under 19 years or an adolescent population defined as individuals aged 9–18 years old living in a European country where HPV vaccines were licensed were included

Summary

Introduction

Since the introduction of HPV vaccines, several studies have been conducted in different countries to assess HPV knowledge and vaccine acceptance. According to the latest data reported for Europe, an estimated 680,344 to 844,391 genital warts; 216,636 to 413,977 cases of high-grade cervical intraepithelial lesions (CIN2+); 31,130 cervical cancer cases; 6786 head and neck cancers; and 10,076 cancers in vulva, vagina, penis, and anus attributable to the aforementioned nine HPV types [2] are diagnosed annually in males and females. Some of these conditions, such as anal or oropharyngeal cancer, have increased recently [5]

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