Abstract
Given the growing craze for dietary supplements, it is essential to critically examine the safety concerns surrounding their usage. There have been several cases of contaminated food-related mishaps in spite of numerous rules and laws in existence. We thus made an effort to find the existence of five antihistamines and four hypertensive in herbal items from the Vietnamese market, given the rising severity of this issue. High-performance thin-layer chromatography (HPTLC) was used to screen 32 samples, which were typical of the many kinds of herbal products. The investigation included both intra- and inter-day precision as well as repeatability. For all analytes, the devised technique was proven to be exact, with %RSD lower than 6%. The LOD and LOQ of nine compounds were determined to be in the range of 0.15–0.30 mg/g and 0.50–1.00 mg/g, respectively (solid matrix sample); 0.075–0.150 mg/g; and 0.25–0.50 mg/g (liquid matrix sample). The intra-day variation's percentage RSD varies from 1.40 to 5.10. Nonetheless, the inter-day variation's percentage RSD fell between 3.10 and 6.60. As a result, the procedure may be used to analyze herbal dietary supplement samples that are in circulation in order to quality control the herbal products on the Vietnamese market.
Published Version
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