Abstract
Tisagenlecleucel is a chimeric antigen receptor T-cell therapy for B-cell acute lymphoblastic leukaemia and diffuse large B-cell lymphoma, which has achieved reimbursement using OBR schemes in Europe and the US. OBR schemes are becoming popular to manage uncertainty and alleviate the financial burden on healthcare systems when adopting high-cost medicines. This research will compare reimbursement models that have been developed for tisagenlecleucel.
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