Abstract
Liquorice has being used as a folk medicine for pharmacological activities in China. The phytochemicals and antioxidant activity of liquorice extract were investigated, total phenolics (TP) and total flavonoids (TF) contents were determined, and the antioxidant activity of different fractions from the extract was evaluated by scavenging free radicals (ABTS·+, DPPH· and ONOO−). On-line HPLC–ABTS·+ and HPLC–ESI–MS/MS analysis were applied to screen and identify free radical scavengers of liquorice extract. The results indicated that ethyl acetate and n-butanol fractions of the extract contained higher contents of TP and TF and exhibited stronger antioxidant activities. Thirteen compounds in the extract were identified as glycyrrhizic acid, liquorice-saponin G2, liquiritin, licuraside, ononin, glycycoumarin, isoglycyrol, liquiritin apioside, liquorice-glycoside A, liquorice-glycoside B, licoric-saponin A3, isoliquiritin apioside and isolicoflavonol, in which ten compounds were free radical scavengers. In addition, glycyrrhizic acid, ononin and liquiritin were quantitatively analyzed. These findings revealed that liquorice extract had potential antioxidant activity and could be utilized as a nutraceutical resource.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
