HP-4-1 Improvement of Sexual Functions in Men With Benign Prostatic Hyperplasia With Long-Term Use of the Serenoa Repens Extract

Abstract

To evaluate the effectiveness of Serenoa repens (SR) extract in the treatment of erectile and ejaculatory function disorders in individuals with BPH. The study included 34 patients with BPH and various sexual dysfunctions who received SR extract in monotherapy 320 mg per day for 12 months. In all patients who received SR extract, after 12 months there was a significant increase in all integrative scores of the IIEF. The average score “erectile function” increased from 14.28±0.98 to 24.86±0.23 (p< 0.01), “satisfaction with sexual intercourse” - from 7.24±0.31 to 13.52±0.58 (p< 0.05), “orgasm” - from 4.92±0.14 to 9.31±0.38 (p< 0.05), “total satisfaction” - from 4.01±0 , 29 to 8.13±0.32 (p< 0.01), which in percentage terms indicated an increase in scores by an average of 2 times. Enhancement of libido, increase in sexual desire in dynamics, according to IIEF, averaged 58.2%. The effectiveness of SR monotherapy in the restoration of erectile function score averaged 83.3%. The effect of SR was studied separately in 23 men with secondary PEj due to BPH (disease duration on average 5.4±0.4 years). Patients were divided into groups depending on the duration of sexual intercourse before treatment: ejaculation before insertion of the penis into the vagina in 2 (8.7%) patients (group 1); up to 30 seconds - in 10 (43.5%) (group 2); up to 60 seconds - in 8 (34.8%) patients (group 3); up to 120 seconds - in 3 (13.0%) (group 4).