How Websites and Mobile Applications Wrongly Calculate eGFR by MDRD Equation

Abstract

Equations to estimate glomerular filtration rate (GFR) are routinely used for the diagnosis and classification of chronic kidney diseases (CKDs). Modification of Diet in Renal Disease (MDRD) equation is an old one and has been replaced in many countries by CKD Epidemiology Collaboration (CKD-EPI) equation, but MDRD is still available in routine practice worldwide, especially in developing countries. Many users of MDRD, don’t know that it has two different versions (equations). This idea makes confusion in practice and affected the developers of this equation in internet websites and mobile applications. In this review, we will focus on this dilemma and try to solve it by explaining the basics of these two versions, and when I can choose each version, then the reflection of this issue on about 105 websites/Applications from different countries around the world. After that, we will give recommendations for both developers and seekers of this equation about overcoming this debate.