Abstract

Parkinson’s disease (PD) is a common neurological disease. Due to its chronic and progressive character, it is marked by a slow depletion in dopaminergic transmission in the basal ganglia. Since its original description, new findings have hatched; making it, by many specialists, as a systemic disease that starts with hyposmia, changes in the REM sleep phase and intestinal constipation, years before the motor manifestations [1].

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