Abstract

Adverse drug reactions (ADRs) and Drug-Drug interactions (DDIs) remain an important clinical problem in modern healthcare systems, particularly, with the rising complexity of therapeutics, ageing population and multi-morbidity. There is no doubt that the unpleasant impacts resulting from inaccurate or wrong dose which used in prophylaxis or treatment, will cause significant harm to the patient. Therefore, it is important to shed the light on these such cases in order to avoid further harm consequences. ADRs can be happened due to involvement of T-lymphocyte or IgE-mediated allergy. Hypersensitivity reactions have been highlighted in recent years, so, allergy test is a necessary step before taking medications that may cause hypersensitivity react ion. This article summarizes some of the key facts about ADRs and explores aspects related to their prevention, diagnosis, reporting and management in current clinical practice using strategies, procedures and tools for quality improvement to avoid any probable mistakes. The article will also illustrate the key role of healthcare practitioners in documenting and reporting the ADRs correctly.

Full Text
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