Abstract
Biology and medicine are very rich knowledge domains in which already at an early stage in their scientific development it was realised that without a proper way to organise this knowledge they would inevitably turn into chaos. Early examples of organisation attempts are for example “De Rerum Natura (On the Nature of Things)” by Titus Lucretius Carus (99–55 BC), which explains the natural and physical world as known at the time, and of course the work “Systema Naturae” by Carl Linnaeus published in 1735. The latter book can be seen as the clear recognition of the need of using systematic methods, here principles of taxonomic organisation, to classify nature. As soon as one considers using systematic methods, computer-based representations and algorithms come to mind.
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