How to measure structural and functional neuronal networks using neuroimaging

Abstract

Event Abstract Back to Event How to measure structural and functional neuronal networks using neuroimaging Leonardo Bonilha1* 1 Medical University of South Carolina, United States This is an abstract for the the symposium on Neuronal networks in language and aphasia (Leonardo Bonilha) Neuroimaging has provided an important window into the structure and function of the human brain in vivo. Quantitative imaging permits the assessment of neurobiological mechanisms underlying recovery, and they also provide biomarkers to inform therapists about potential treatment responders. In this presentation, we will discuss the main tools used for neuroimaging analyses in the context of language processing and, more specifically, impaired function after brain injury. Building on classical neuropsychological models of brain injury – functional relationships from post-mortem studies, we will discuss more modern approaches to lesion symptom mapping including voxel-based lesion symptom mapping and connectome –lesion symptom mapping. We will discuss caveats related to spatial normalization of injured brains, and alternatives to overcome these challenges. We will also discuss how these apply to resting state and task based functional MRI and we will present and discuss the software packages produced including MRIcro, MRIcron, MRIcroGL and Surfice. These are familiar packages to most of the scientific community (MRIcron has consistently ranked among the most commonly downloaded software from the NIH Neuroimaging Informatics Tools and Resources Clearinghouse). Finally, we will discuss future avenues for collaborative datsets and modern approached combing multiple imaging modalities. Keywords: MRI, Diffusion Tensor Imaging, functional MRI, neural networks dynamics, Multimodal Imaging Conference: Academy of Aphasia 56th Annual Meeting, Montreal, Canada, 21 Oct - 23 Oct, 2018. Presentation Type: symposium Topic: not eligible for a student prize Citation: Bonilha L (2019). How to measure structural and functional neuronal networks using neuroimaging . Conference Abstract: Academy of Aphasia 56th Annual Meeting. doi: 10.3389/conf.fnhum.2018.228.00062 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 30 Apr 2018; Published Online: 22 Jan 2019. * Correspondence: Dr. Leonardo Bonilha, Medical University of South Carolina, Charleston, United States, bonilha@musc.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Leonardo Bonilha Google Leonardo Bonilha Google Scholar Leonardo Bonilha PubMed Leonardo Bonilha Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.