Abstract
In this review, we discussed the method and the clinical relevance of bladder sensory abnormality in peripheral nerve diseases. Urodynamic first-sensation-volume increase is the most striking bladder sensory abnormality in peripheral nerve diseases, particularly diabetic polyneuropathy. Decreased bladder sensation might occur unwittingly even by patients. However, bladder sensory abnormality is clinically relevant, since it may lead to overflow urinary incontinence due to retention, secondary pyelonephritis, and kidney dysfunction. A small proportion of patients have increased bladder sensation, which leads to urinary urgency and frequency without detrusor overactivity.
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