Abstract
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Highlights
THE IMPORTANCE OF SCALEBiobanking is essential for science-based health care solutions in the 21st century
The strength of BBMRI-NL lies in its broad spectrum of participating biobanks, ranging from specialized small-scale clinical to large, professionally operated population-based cohorts
Genomic enrichment is a major aim in 52% of the projects, ranging from isolation and quantification of DNA in biological material that is already available to Genome Wide Association analysis, construction of Tissue Micro-Arrays and Whole-exome sequencing
Summary
Biobanking is essential for science-based health care solutions in the 21st century. In order to develop better diagnostics, treatments and cures for diseases a deeper understanding is needed of genetic and environmental pathways causing disease, including mechanisms that protect people from becoming ill. Scientific research aimed at these issues depends on the availability of a broad spectrum of high quality human biological samples related to health and disease, accompanied by clinical, environmental and lifestyle data. The Dutch National Roadmap for Large-scale Research Facilities which was published later in 2008 indicated the Dutch node of BBMRI, BBMRI-NL, as top-priority [4]. It received 22.5 million Euros for its initial three year period from NWO, The Netherlands Organization for Scientific Research. In this article we outline the Dutch experience in biobanking: how a national network of biobanks, BBMRI-NL, was set up in the Netherlands and the results achieved since its initiation in 2009
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