Abstract
ious miscellaneous causes in 10.3% (89) of patients. Among the causes of chronic liver disease, alcohol was the most common 57.1% (539), followed by hepatitis viruses (hepatitis B and hepatitis C) 15.9% (150), cryptogenic 9.5% (90) and others 17.3% (164) of cases. Infection was documented in 29% (125/433) of patients during hospitalisation. The chronic liver failure-sequential organ failure assessment (CLIF-SOFA) included liver failure in 58.1% (538/925), renal 62% (572/929), cerebral 11% (95/832), coagulation 32.7% (265/809), respiratory 14.1% (66/466) and circulatory failure in 14.2% (48/338). A total of 45% (430/949) of patients died, mean duration of hospital stay was 10.6 9.4 days. Conclusions: Alcohol was the commonest aetiology of underlying chronic liver diseases and continuous consumption was also the commonest cause of ACLF in the Indian subcontinent. Liver failure and renal failure were the most frequent organ failures. Within a mean hospital stay of around 10 days, 45% died.
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